Entrepreneur Dr James McIlroy is founder & CEO of EnteroBiotix, an award-winning and rapidly expanding biotechnology company that he started while at medical school. EnteroBiotix is focused on a whole new field of science and medicine, using the body’s own microorganisms to prevent and treat debilitating infections and diseases. James joins me to discuss practicalities of managing an incredibly busy workload, how he learned to delegate and focus on high yield outcomes - and why he has decided that now is the time to step back as CEO and bring someone in to help him scale the business, while he continues his medical training.

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Incredibly inspirational "mad scientist", theoretical neuroscientist, AI inventor and entrepreneur Dr Vivienne Ming advises a listener overwhelmed by ideas and possibilities that finding your purpose is more important than forcing yourself to focus and be someone you're not. She talks about the importance of recognising your weaknesses and having a compensatory strategy for overcoming them and why hiring complementary collaborators is essential to entrepreneurial success and to delivering solutions that bring real value to people. As a leader and creative collaborator, she sees her number one job as explaining the why - then to simply be a resource to enable her team to be even more successful.

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CEO, Chairman and NXD Kenny Fraser advises a solo founder having an existential crisis about what their role as CEO should be, urges entrepreneurs not to neglect their own personal and professional development - and advises a founder to forget everything they've heard about sales and commissions, in order to ensure their team remains aligned to common goals and a shared compensation structure. Great insights on people, teams, incentives and the growth mindset.

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What are the risks and rewards of working in a startup? And what 3 things do startup employees most wish their CEO would learn? I'm joined by Regina Berengolts, my head of data in my last startup, and now leading the data science team at a high growth TV analytics scaleup for the employee perspective on getting the people part of startups right. We talk about the startup mindset we look for in employees, whether a startup job is right for you, CEO transparency and the questions potential hires should be ready to ask of founders. We also get into the importance of knowing what you are hiring for before you bring people in and why you probably don't actually need to hire a data scientist yet.

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My three-time co-founder and product lead, Stephen Budd, shares some hard-learned lessons on what non-technical founders need to know in order to successfully lead a technology or software based startup. We talk co-founders, CTOs, product build and outsourcing software development before diving into all things co-founders. When you need a co-founder, where to find them, choosing friends vs strangers, how to set up agreements, who should be CEO and what to do if it is all going horribly wrong with your co-founder.

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How do you attract talent to your startup when resources are limited? Kirsty Mackenzie, founder, award-winning entrepreneur and recruitment specialist, explains how to find, reward and retain employees in your startup. She explains how to build your very first team, what to do if you get it wrong, why you need to think very carefully about company values and the skills you need before you hire and the different things to think about once your business grows. 

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As businesses grow, they hit key inflection points that mean the old tactics don't work anymore. The interplay of people, structures and process have to be updated as a startup develops and so you have to change how you and your people operate within your company. Mark gives very practical advice on how to recognize and survive these inflection points that increase frustration and reduce productivity. He explains how devolving decision making, growing your own people, encouraging them to look outside for inspiration and setting an expectation of world-class excellence maximizes the chances of surviving the organizational challenges that come with growth.

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